Previously healthy adults among septic patients: Population-level epidemiology and outcomes
Main finding · Short-term mortality, overallResult — go to the resultAdjusted odds ratio 0.62 95% CI 0.57–0.69Authors' conclusion
Previously healthy septic patients had lower short-term mortality compared to those with comorbid conditions.
Study context
- Population
- Hospitalizations aged ≥18 years with a diagnosis of sepsis in Texas, 2018–2019
- Participants
- 120,371 sepsis hospitalizations
- Exposure
- Previously healthy vs comorbidities
- Previously healthyn = 6,611
- Outcome
- Short-term mortality (in-hospital mortality or discharge to hospice)
Methodological detailsstatewide dataset, hierarchical models
- Statewide dataset
- Hierarchical models
Main finding
Short-term mortality, overall
Adjusted odds ratio
0.62
95% CI 0.57–0.69
By group
Previously healthy vs Comorbidities
aOR 0.62 (95% CI 0.57–0.69)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Short-term mortality, community-onset sepsis (subgroup)
Short-term mortality, hospital-onset sepsis (subgroup)
- Short-term mortality, community-onset sepsis (subgroup): 105,455 (87.6%) had community-onset sepsis
Short-term mortality, community-onset sepsis (subgroup)
- Adjusted findings consistent with the primary analysis
Short-term mortality, hospital-onset sepsis (subgroup)
- Adjusted findings consistent with the primary analysis
Original publication
Previously healthy adults among septic patients: Population-level epidemiology and outcomes. J Crit Care. Published 15 September 2023. doi:10.
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