Prognostic Factors Associated With Intracranial Hemorrhage and Ischemic Stroke During Venovenous Extracorporeal Membrane Oxygenation: A Systematic Review
Authors' conclusion
This systematic review demonstrates that abnormalities and changes in blood gas parameters from pre- to post-venovenous ECMO cannulation are probably associated with increased risk of ICH.
Study context
- Population
- Adults undergoing venovenous extracorporeal membrane oxygenation (ECMO)17 studies
- Outcome
- Prognostic factors for ICH and ischemic stroke during venovenous ECMO
Methodological detailsGRADE certainty assessment, Quality in Prognostic Studies risk of bias
- GRADE certainty assessment
- Quality in Prognostic Studies risk of bias
Pooled result
As reported in the abstract
Predictors of ICH and ischemic stroke
- Lower pH before venovenous ECMO associated with increased intracranial hemorrhage (ICH) risk (5 studies, moderate certainty)
- Greater decreases in PaCO2 pre- to post-cannulation associated with increased ICH risk (5 studies, moderate certainty)
- No predictor of ischemic stroke identified in ≥2 studies (4 studies)
Original publication
Prognostic Factors Associated With Intracranial Hemorrhage and Ischemic Stroke During Venovenous Extracorporeal Membrane Oxygenation: A Systematic Review. Crit Care Med. Published 11 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →