Hemodynamics, fluids & transfusion

Prognostic Model for Vasopressor Requirement After Retroperitoneal Adrenalectomy for Pheochromocytoma: A Retrospective Study

J Cardiothorac Vasc AnesthPublished Retrospective observational study

Authors' conclusion

A MaxSBP >195 mmHg, baseline adrenergic activity >5.1-fold increase in the upper limit of normal values, and baseline CAD could predict postresection requirements for vasoactive support.

Study context

Population
Adults who underwent unilateral adrenalectomy for pheochromocytoma at a university hospital, October 2015 to February 2020
Participants
201 adults
Outcome
Postoperative hypotension requiring vasopressor support
Methodological detailssingle-center
  • Single-center

Main finding

As reported in the abstract

Postoperative vasopressor requirement
Odds ratio (95% CI)P value
Baseline CAD
6.21(2.48–15.52)
P = 0.0001
maxSBP >195 mmHg
3.71(1.53–8.95)
P = 0.0035
>5.1-fold increase in upper limit of normal for baseline adrenergic activity
4.9(1.93–12.55)
P = 0.0008
Postoperative vasopressor requirement, overall
39 (19.4%)

Observational data: associations, not effects.

Further findings

Discrimination of the predictive model

AUC
0.804 (95% CI 0.742-0.856)

Original publication

Prognostic Model for Vasopressor Requirement After Retroperitoneal Adrenalectomy for Pheochromocytoma: A Retrospective Study. J Cardiothorac Vasc Anesth. Published 4 March 2023. doi:10.1053/j.jvca.2023.02.043

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