Hemodynamics, fluids & transfusion
Prognostic Model for Vasopressor Requirement After Retroperitoneal Adrenalectomy for Pheochromocytoma: A Retrospective Study
Authors' conclusion
A MaxSBP >195 mmHg, baseline adrenergic activity >5.1-fold increase in the upper limit of normal values, and baseline CAD could predict postresection requirements for vasoactive support.
Study context
- Population
- Adults who underwent unilateral adrenalectomy for pheochromocytoma at a university hospital, October 2015 to February 2020
- Participants
- 201 adults
- Outcome
- Postoperative hypotension requiring vasopressor support
Methodological detailssingle-center
- Single-center
Main finding
As reported in the abstract
Postoperative vasopressor requirement
Odds ratio (95% CI)P value
Baseline CAD
6.21(2.48–15.52)
P = 0.0001maxSBP >195 mmHg
3.71(1.53–8.95)
P = 0.0035>5.1-fold increase in upper limit of normal for baseline adrenergic activity
4.9(1.93–12.55)
P = 0.0008- Postoperative vasopressor requirement, overall
- 39 (19.4%)
Observational data: associations, not effects.
Further findings
Discrimination of the predictive model
- AUC
- 0.804 (95% CI 0.742-0.856)
Original publication
Prognostic Model for Vasopressor Requirement After Retroperitoneal Adrenalectomy for Pheochromocytoma: A Retrospective Study. J Cardiothorac Vasc Anesth. Published 4 March 2023. doi:10. 1053/ j. jvca. 2023. 02. 043
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