Respiratory failure & ventilation
Psychiatric patients' intensive care admission characteristics, weaning from mechanical ventilation and sedative drug use: A single center retrospective case-control study
Authors' conclusion
Critically ill PPC had higher mortality rates than their matched counterparts. They also had higher MV rates and were more difficult to wean.
Study context
- Population
- Critically ill ICU patients, single centre, 6 years214 per group
- Participants
- 214 vs 214
- Comparison
- PPC vs Without PPC
- PPCn = 214
- Without PPCn = 214reference
- Outcome
- Adjusted mortality rates
Methodological detailssingle-centre, sex and age matched 1:1
- Single-centre
- Sex and age matched 1:1
Main finding
As reported in the abstract
Adjusted mortality
PPC vs Without PPCOdds ratio (95% CI)P value
ICU mortality 14.0% vs 4.7%
3.058(1.380–6.774)
P = 0.006In-hospital mortality 26.6% vs 13.1%
2.639(1.496–4.655)
P = 0.001Observational data: associations, not effects.
Secondary outcomes
MV rates
P = 0.011
Self-extubation
P = 0.004
Success of planned extubations
P < 0.001
| Outcome | PPC | Without PPC | P value |
|---|---|---|---|
| >2 weaning attempts | 29.4% | — not stated in the abstract | P < 0.001 |
| >2 sedative drugs in 48 h pre-extubation | 39.2% | — not stated in the abstract | P = 0.026 |
— not stated in the abstract
Propofol in 24 h pre-extubation
- PPC received more propofol
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Psychiatric patients' intensive care admission characteristics, weaning from mechanical ventilation and sedative drug use: A single center retrospective case-control study. J Crit Care. Published 20 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →