Respiratory failure & ventilation
Pulmonary embolism impacts clinical outcomes of intubated patients with acute respiratory distress syndrome related to COVID-19
Authors' conclusion
The occurrence of PE in patients with ARDS due to COVID-19 had a significant impact on clinical outcomes. They had fewer ventilator-free days, longer duration of IMV, and longer ICU and hospital lengths of stay. However, pulmonary embolism was not associated with higher mortality.
Study context
- Population
- Intubated patients with acute respiratory distress syndrome (ARDS) due to COVID-19 admitted to the intensive care unit (ICU) of Geneva University Hospitals, March 9, 2020–May 31, 2022
- Participants
- 370 patients
- Exposure
- Pulmonary embolism (PE) vs no PE
- PEn = 58
- No PEn = 312reference
- Outcome
- Ventilator-free days
- Follow-up
- First 28 days after ICU admission
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
P < 0.001
Observational data: associations, not effects.
Further findings
Mortality · did not differ significantly
P = 0.72
- Prevalence of PE
- 15.7% · 58
- Prevalence of PE: of 370 intubated patients
Duration of IMV, ICU and hospital LOS
- Significantly longer with PE
Need for ECMO support
- Similar in both groups
Original publication
Pulmonary embolism impacts clinical outcomes of intubated patients with acute respiratory distress syndrome related to COVID-19. Anaesth Crit Care Pain Med. Published 24 January 2024. doi:10.
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