Quantra analyzer with the QStat® Cartridge compared with conventional laboratory tests during postpartum hemorrhage: a retrospective cohort study (2021–2023)
Authors' conclusion
Quantra parameters during PPH provide rapid and reliable detection of blood clotting disorders.
Study context
- Population
- Obstetric patients with PPH with Quantra QStat assessment160 paired tests analysed
- Participants
- 130 patients
- Exposure
- Quantra QStat vs paired laboratory tests
- Outcome
- Correlations between Quantra QStat measurements and standard laboratory tests during PPH
Methodological detailsobservational
- Observational
Main finding
As reported in the abstract
Correlation (rs) of Quantra QStat with laboratory tests
Rs
0.61
P < 0.001
Clotting time (CT) vs aPTT ratio
Rs
0.75
P < 0.001
PCS vs platelet count
Rs
0.84
P < 0.001
FCS vs Clauss fibrinogen (CF)
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| FCS for diagnosing CF ≤2 g/L | FCS AUC 0.96 · P P <0.0001 · optimal cut-off 2 hPa |
| PCS for diagnosing platelet count < 80,000/μL | PCS AUC 0.94 · P P <0.0001 · optimal cut-off 11.5 hPa · sensitivity 0.89 · specificity 0.88 |
| CT for diagnosing aPTT ratio >1.2 or >1.5 | CT AUC (aPTT ratio >1.2) 0.94 · P (aPTT ratio >1.2) P <0.001 · AUC (aPTT ratio >1.5) 0.92 · P (aPTT ratio >1.5) P <0.0001 · optimal cut-offs 127 and 133 seconds |
Original publication
Quantra analyzer with the QStat® Cartridge compared with conventional laboratory tests during postpartum hemorrhage: a retrospective cohort study (2021–2023). Int J Obstet Anesth. Published 25 January 2025. doi:10.
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