Cardiac arrest & resuscitation
Randomized feasibility trial of remote ischemic conditioning to enhance resuscitation (RICE)
Authors' conclusion
Application of RIC to patients resuscitated from CA and transported to an ED is feasible and safe.
Study context
- Population
- Adults with non-traumatic out-of-hospital cardiac arrest (OHCA) resuscitated and transported to hospital
- Participants
- 30 adults
- Comparison
- Remote ischemic conditioning (RIC) plus standard care vs standard care
- RICn = 16
- Standard caren = 14reference
- Primary endpoint
- Attrition: proportion enrolled and not on allocated therapy for the study duration
Methodological detailsfeasibility trial, masked allocation, exception from informed consent
- Feasibility trial
- Masked allocation
- Exception from informed consent
Primary result
As reported in the abstract
Attrition
All enrolled patients completed allocated intervention (attrition)
0%
Secondary outcomes
Survival to discharge · summarized descriptively
Median
| Outcome | RIC | Standard care |
|---|---|---|
| Rankin score at discharge | 6 (IQR 1–6) | 6 (IQR 1.5–6) |
Safety
- Transient occlusion of upper extremity IV line (resolved on cuff repositioning) — RIC
- 6%
Original publication
Randomized feasibility trial of remote ischemic conditioning to enhance resuscitation (RICE). Resuscitation. Published 13 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →