Pediatric anesthesia & critical care
Recovery Trajectories in Children Requiring 3 or More Days of Invasive Ventilation
Authors' conclusion
Impairments in HRQL and functional status as well as health resource use were common among children with acute respiratory failure. Early therapy consultation was a modifiable characteristic associated with shorter duration of worsened HRQL in older patients.
Study context
- Population
- Children without preexisting tracheostomy receiving ≥3 days of invasive ventilation in a quaternary children's hospital PICU, surviving hospitalization, with ≥1 postdischarge data collection
- Participants
- 144 children
- Outcome
- HRQL (proxy-report Pediatric Quality of Life Inventory) and functional status (Functional Status Scale) recovery trajectories
- Follow-up
- 1, 3, 6 and 12 months after hospital discharge
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Worsened health-related quality of life (HRQL) at 1 month (68 of 122)
56%
New functional impairment at 1 month
35
29%
Worsened HRQL at 3 months
54
46%
New functional impairment at 3 months
24
20%
Observational data: associations, not effects.
Further findings
Risk factors for HRQL recovery (interaction forests)
- Therapy consultation within 3 days of intubation associated with better HRQL recovery in older patients and those with better preillness physical HRQL
Health resource use during postdischarge year · 12 months
- ED visit or hospitalization
- 76 (53%)
- Newly received physical, occupational or speech therapy
- 62 (43%)
Original publication
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