Haemodynamics, fluids & transfusion
Reduction of Central Venous Pressure in Elective Robotic and Laparoscopic Liver Resection: The PRESSURE Trial-A Randomized Clinical Study
Authors' conclusion
MILR without CVP reduction during liver transection is safe and is not associated with increased intraoperative blood loss.
Study context
- Population
- Patients undergoing elective minimally invasive (robotic or laparoscopic) liver surgery, August 2020 to April 2023112 analysed
- Participants
- 120 patients
- Comparison
- No central venous pressure (CVP) reduction vs CVP reduction
- Primary endpoint
- Total intraoperative blood loss
Methodological detailsdouble-blinded
- Double-blinded
Primary result
As reported in the abstract
P = 0.30
Further findings
CVP during resection
P < 0.001
Blood loss during parenchymal transection · no difference
P = 0.39
90-day mortality · comparable
P = 0.68
Safety
Total morbidity · comparable
P = 0.77
Intraoperative hemodynamic instability · less frequent with no CVP reduction
P = 0.03
Original publication
Reduction of Central Venous Pressure in Elective Robotic and Laparoscopic Liver Resection: The PRESSURE Trial-A Randomized Clinical Study. Ann Surg. Published 8 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →