Pediatric anesthesia & critical care
Regional Analgesia in Pediatric Cardiothoracic Surgery: A Bayesian Network Meta-Analysis
Pooled result · Opioid consumption within 24 h postoperativelyResult — go to the resultWMD −0.97 mg/kg morphine equivalent 95% CrI −1.1 to −0.84Authors' conclusion
Regional anesthesia revealed significant opioid-sparing effects following pediatric cardiothoracic surgery.
Study context
- Population
- Pediatric patients undergoing cardiothoracic surgery
- Participants
- 1,602 patients · 24 studies
- Comparison
- 13 regional blocks vs control
- Outcome
- Opioid consumption
- Follow-up
- 24 hours postoperatively
Methodological detailsBayesian NMA
- Bayesian NMA
Pooled result
Opioid consumption within 24 h postoperatively
WMD
−0.97 mg/kg morphine equivalent
95% CrI −1.1 to −0.84
Thoracic retrolaminar block vs Control
WMD −0.97 mg/kg morphine equivalent (95% CrI −1.1 to −0.84)
As reported in the abstract
Further pooled results
Pain scores
- No significant difference between any block and control at any time point, except thoracic retrolaminar block at 0 h postoperatively
Time to first rescue analgesic
- All regional blocks prolonged time to first rescue analgesic; longest with pectoral nerve block
Safety
PONV
- Lowest incidence with epidural anesthesia, followed by transversus thoracis muscle plane block
Original publication
Regional Analgesia in Pediatric Cardiothoracic Surgery: A Bayesian Network Meta-Analysis. J Cardiothorac Vasc Anesth. Published 9 January 2025. doi:10.
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