Cardiothoracic & vascular anesthesia

Safety and feasibility of ultrasound-guided serratus anterior plane block and intercostal nerve block for management of post-sternotomy pain in pediatric cardiac patients: A prospective, randomized trial

Anaesth Crit Care Pain MedPublished Randomised controlled trial

Authors' conclusion

Ultrasound-guided SAPB and ICNB provided safe and satisfactory early postoperative analgesia while reducing opioid consumption following sternotomy in pediatric patients.

Study context

Population
Children after sternotomy for cardiac surgery, in the cardiothoracic ICU
Participants
60 children
Comparison
Ultrasound-guided SAPB or ICNB plus IV opioids vs IV opioids alone
Primary endpoint
Opioid requirement
Follow-up
First 24 h after surgery
Methodological detailsprospective
  • Prospective

Primary result

As reported in the abstract

Cumulative opioid dose · 24 h

P = 0.000

Further findings

OutcomeP value
Tracheal extubation timeSAPB and ICNB vs C · shorter in block groups, not statistically significantP = 0.177

FLACC scale values · 0, 1, 3, 6, 12, and 24 h post-extubation

Similar in the three groups

Safety

Mean, mg.L-1

OutcomeSAPBICNB
Peak plasma ropivacaine concentration · 10 min post-blockThen slowly decreased2.1 (SD 0.8)1.8 (SD 0.7)

Complications associated with regional anesthesia

No noticeable complications observed

Original publication

Safety and feasibility of ultrasound-guided serratus anterior plane block and intercostal nerve block for management of post-sternotomy pain in pediatric cardiac patients: A prospective, randomized trial. Anaesth Crit Care Pain Med. Published 24 June 2023. doi:10.1016/j.accpm.2023.101268

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