Cardiothoracic & vascular anesthesia
Relationship between endotoxin core and staphylococcal antibody levels and outcome following transcatheter aortic valve implantation (TAVI)
Authors' conclusion
This study indicates that there is little association between post-procedural length of stay in hospital following TAVI and pre-procedural antibody levels to endotoxin or staphylococcus, unlike that seen with surgical patients.
Study context
- Population
- Adults scheduled for elective TAVI112 sera assayed
- Participants
- 122 adults
- Exposure
- Pre-procedure antibody level quartiles
- Outcome
- Post-procedure LOS in hospital
Methodological detailssub-group of a larger observational cohort study
- Sub-group of a larger observational cohort study
Main finding
As reported in the abstract
Correlation of antibody levels with LOS
- Teichoic acid correlation with length of stay (LOS) r2
- 0.02
- Alpha-toxin correlation with LOS r2
- 0.02
- EndoCAb correlation with LOS r2
- < 0.02
- Combined rank correlation with LOS r2
- 0.03
- Median LOS across quartiles, teichoic acid (ANOVA)
- p = 0.153
- Median LOS across quartiles, alpha-toxin (ANOVA)
- p = 0.332
- Median LOS across quartiles, EndoCAb (ANOVA)
- p = 0.848
- Median LOS across quartiles, combined rank (ANOVA)
- p = 0.374
Observational data: associations, not effects.
Secondary outcomes
Post-operative infections across antibody quartiles
- No differences, teichoic acid (ANOVA)
- P = 0.994
- No differences, alpha-toxin (ANOVA)
- P = 0.962
- No differences, EndoCAb (ANOVA)
- P = 0.918
- No differences, combined rank (ANOVA)
- P = 0.855
Original publication
Relationship between endotoxin core and staphylococcal antibody levels and outcome following transcatheter aortic valve implantation (TAVI). Perioper Med (Lond). Published 14 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →