Hemodynamics, fluids & transfusion
Renal medullary oxygenation during laparoscopic vs open surgery: the impact of blood pressure management—a pilot randomized controlled trial
Authors' conclusion
Surgical approach and intraoperative blood pressure targets significantly impact urinary oxygenation.
Study context
- Population
- Patients undergoing laparoscopic or open surgery under GA
- Participants
- 43 patients
- Comparison
- High vs usual mean arterial pressure (MAP) target during laparoscopic or open surgery
- Laparoscopicn = 20
- Openn = 23
- Primary endpoint
- Continuous urinary oxygenation (PuO2), surrogate of renal medullary PO2
Methodological detailsretrospectively registered
- Retrospectively registered
Primary result
As reported in the abstract
PuO2
Mean difference
11 ± 1 mmHg
P < 0.001
Open vs Laparoscopic · usual MAP target; higher PuO2 with open surgery
Mean difference
7 ± 1 mmHg
P < 0.001
High MAP vs Usual MAP · laparoscopic surgery; higher PuO2 with high MAP
Mean difference
7 ± 1 mmHg
P < 0.001
Usual MAP vs High MAP · open surgery; higher PuO2 with usual MAP
- PuO2 decrease during laparoscopic surgery, usual MAP target
- - 51%
- PuO2 decrease during open surgery, usual MAP target
- - 49%
Original publication
Renal medullary oxygenation during laparoscopic vs open surgery: the impact of blood pressure management—a pilot randomized controlled trial. J Clin Monit Comput. Published 13 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →