Respiratory impact of local anaesthetic volume after interscalene brachial plexus block with extrafascial injection: a randomised controlled double-blinded trial
Authors' conclusion
A low volume of local anaesthetic injected extrafascially reduced the rate of hemidiaphragmatic paralysis, but at the expense of a shorter duration of analgesia compared with standard-dose extrafascial anaesthetic injection.
Study context
- Population
- ASA 1–3 patients scheduled for elective shoulder surgery under GA
- Participants
- 60 participants
- Comparison
- Extrafascial ISB with ropivacaine 0.75% 10 ml vs 20 ml
- Primary endpoint
- Hemidiaphragmatic paralysis (diaphragmatic excursion reduction >75%, M-mode ultrasonography)
- Follow-up
- 30 min after the procedure
Methodological detailsdouble-blinded
- Double-blinded
Primary result
As reported in the abstract
30 min
P < 0.001
Secondary outcomes
Duration of analgesia
P < 0.01
i.v. morphine consumption · 24 h after surgery
P = 0.03
Original publication
Respiratory impact of local anaesthetic volume after interscalene brachial plexus block with extrafascial injection: a randomised controlled double-blinded trial. Br J Anaesth. Published 23 January 2025. doi:10.
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