Anaesthetic drugs & techniques

Response of the GE Entropy™ monitor to neuromuscular block in awake volunteers

Br J AnaesthPublished Mechanistic study

Authors' conclusion

The GE Entropy™ monitor requires muscle activity to generate correct values in an awake subject.

Study context

Population
Awake volunteers given NMBA (EEGs from original BIS study replayed to an Entropy monitor)9 rocuronium and 10 suxamethonium trials
Comparison
Rocuronium vs Suxamethonium
Outcome
State Entropy and Response Entropy during NMB
Methodological detailsEEG playback via calibrated electronic system, each EEG replayed 30 times
  • EEG playback via calibrated electronic system
  • Each EEG replayed 30 times

Main finding

As reported in the abstract

GroupValueTrials with State Entropy <60
Rocuronium8 eventseight of nine
Suxamethonium9 eventsnine of 10

Value

Rocuronium8 events
Suxamethonium9 events

Trials with State Entropy <60

Rocuroniumeight of nine
Suxamethoniumnine of 10

Original publication

Response of the GE Entropy™ monitor to neuromuscular block in awake volunteers. Br J Anaesth. Published November 2023. doi:10.1016/j.bja.2023.08.013

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.