Organ support & nutrition

Resting energy expenditure measured by indirect calorimetry in mechanically ventilated patients during ICU stay and post-ICU hospitalization: A prospective observational study

J Crit CarePublished Prospective observational study

Main finding · Measured REEResult — go to the resultMean difference 3.1 kcal/kg/day CI 1.4–4.9

Authors' conclusion

Critically ill mechanically ventilated patients were shown to have a resting energy expenditure (REE) > 110% of predicted REE on ICU admission day four and thereafter.

Study context

Population
Mechanically ventilated ICU patients, followed until hospital discharge189 ICU indirect calorimetry (IC) measurements
Participants
56 participants
Exposure
Measured resting energy expenditure (REE) vs predicted REE, over ICU and post-ICU ward stay
Outcome
REE measured by indirect calorimetry every three days
Methodological detailsrepeated indirect calorimetry
  • Repeated indirect calorimetry

Main finding

Measured REE

Mean difference

3.1 kcal/kg/day

CI 1.4–4.9

P < 0.001

ICU admission day four vs Baseline
mean difference 3.1 kcal/kg/day (CI 1.4–4.9); P < 0.001

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeMean difference (kcal/kg/day) (CI)P value
Measured REE during post-ICU ward stay vs ICU stayWard REE 33(31-35)kcal/kg/day2.6 (1.2–3.9)P < 0.001
  • Measured REE during post-ICU ward stay vs ICU stay: 44 measurements in 23 patients

Original publication

Resting energy expenditure measured by indirect calorimetry in mechanically ventilated patients during ICU stay and post-ICU hospitalization: A prospective observational study. J Crit Care. Published 12 July 2023. doi:10.1016/j.jcrc.2023.154361

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