Resting energy expenditure measured by indirect calorimetry in mechanically ventilated patients during ICU stay and post-ICU hospitalization: A prospective observational study
Main finding · Measured REEResult — go to the resultMean difference 3.1 kcal/kg/day CI 1.4–4.9Authors' conclusion
Critically ill mechanically ventilated patients were shown to have a resting energy expenditure (REE) > 110% of predicted REE on ICU admission day four and thereafter.
Study context
- Population
- Mechanically ventilated ICU patients, followed until hospital discharge189 ICU indirect calorimetry (IC) measurements
- Participants
- 56 participants
- Exposure
- Measured resting energy expenditure (REE) vs predicted REE, over ICU and post-ICU ward stay
- Outcome
- REE measured by indirect calorimetry every three days
Methodological detailsrepeated indirect calorimetry
- Repeated indirect calorimetry
Main finding
Measured REE
Mean difference
3.1 kcal/kg/day
CI 1.4–4.9
P < 0.001
ICU admission day four vs Baseline
mean difference 3.1 kcal/kg/day (CI 1.4–4.9); P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Mean difference (kcal/kg/day) (CI) | P value | |
|---|---|---|---|
| Measured REE during post-ICU ward stay vs ICU stayWard REE 33(31-35)kcal/kg/day | 2.6 (1.2–3.9) | P < 0.001 | |
| −2024Difference, kcal/kg/day (linear scale) |
- Measured REE during post-ICU ward stay vs ICU stay: 44 measurements in 23 patients
Original publication
Resting energy expenditure measured by indirect calorimetry in mechanically ventilated patients during ICU stay and post-ICU hospitalization: A prospective observational study. J Crit Care. Published 12 July 2023. doi:10. 1016/ j. jcrc. 2023. 154361
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