Cardiothoracic & vascular anesthesia
A Retrospective Pilot Comparison Trial Investigating Clinical Outcomes in Cardiac Surgical Patients Who Received Sugammadex Reversal During 2018 to 2021
Authors' conclusion
This retrospective study suggested that using sugammadex reversal in cardiac surgical patients undergoing cardiopulmonary bypass may result in more patients meeting the Society of Thoracic Surgery benchmark extubation criteria within 6 hours of the end of surgery.
Study context
- Population
- Elective or urgent cardiac surgical patients undergoing CPB (1 cardiac surgeon), extubated within 24 hours of end of surgery, tertiary-care hospital, Evanston, IL, 2018–2021
- Participants
- 358 participants
- Exposure
- Sugammadex reversal vs no sugammadex
- Outcome
- Successful extubation within 6 hours of the end of surgery
- Follow-up
- 6 hours
Methodological detailspropensity matched, single-centre
- Propensity matched
- Single-centre
Main finding
As reported in the abstract
Extubation within 6 hours of end of surgery
P = 0.0428
Observational data: associations, not effects.
Further findings
- Time to extubation — Time to extubation (hours), as printed · statistically significant reduction in the sugammadex group
- (4.72 ± 2.92) v (3.57± 1.96 · P = 0.0098
All other outcomes
- Did not meet statistical significance
Original publication
A Retrospective Pilot Comparison Trial Investigating Clinical Outcomes in Cardiac Surgical Patients Who Received Sugammadex Reversal During 2018 to 2021. J Cardiothorac Vasc Anesth. Published 26 March 2023. doi:10.
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