ICU sedation, delirium & recovery
Right ventricular injury in critically ill patients with COVID-19: a descriptive study with standardized echocardiographic follow-up
Authors' conclusion
RV injury was frequent in COVID-19 patients, occurred within the first two weeks after ICU admission and was most often isolated.
Study context
- Population
- Critically ill patients with COVID-19 admitted to intensive care unit (ICU)
- Participants
- 118 patients · 393 TTE examinations
- Outcome
- Incidence of RV injury during ICU stay
- Follow-up
- Maximum 28 days
Methodological detailsbicentric, standardized TTE follow-up
- Bicentric
- Standardized TTE follow-up
Main finding
As reported in the abstract
At least one RV injury pattern
- Any right ventricular (RV) injury
- 73(62%)
- Isolated RV dilation
- 29(40%)
- RV dysfunction without RV dilation
- 39(53%)
- RV dysfunction with RV dilation
- 10(14%)
- Acute cor pulmonale
- 2(3%)
Observational data: associations, not effects.
Further findings
Day-28 mortality, RV dysfunction with RV dilation or acute cor pulmonale (ACP)
| aHR (95% CI) | P value | ||
|---|---|---|---|
| RV dysfunction with RV dilation or ACPOnly pattern associated with Day-28 mortality | 3.18 (1.16–8.74) | P = 0.03 | |
| 0.10.31310Adjusted hazard ratio (log scale) |
Day-28 mortality, RV injury vs no RV injury
- Higher Day-28 mortality with RV injury
- 27 vs. 7%, p < 0.01
RV injury characteristics and timing
- RV injury isolated
- 82%
- Combined with left ventricular systolic dysfunction
- 18%
- Several RV injury patterns during ICU stay
- 10%
- No RV injury on admission, developed RV injury during ICU stay
- 20(31%)
- No de novo RV injury after Day-14
Original publication
Right ventricular injury in critically ill patients with COVID-19: a descriptive study with standardized echocardiographic follow-up. Ann Intensive Care. Published 23 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →