Hemodynamics, fluids & transfusion
Risk factors for arterial catheter failure and complications during critical care hospitalisation: a secondary analysis of a multisite, randomised trial
Authors' conclusion
AC failure is common with ultrasound-guided insertion associated with lower failure rates.
Study context
- Population
- Adult ICU patients with an arterial catheter (AC)
- Participants
- 664 patients
- Primary endpoint
- All-cause AC failure
Methodological detailsCox proportional hazards and competing-risk models
- Cox proportional hazards and competing-risk models
Primary result
As reported in the abstract
- AC failure
- 173 (26%)
- AC failure incidence rate per 1000 catheter days
- 37
- Ultrasound-assisted insertion, all-cause failure
- adjusted HR 0.43 (0.25, 0.76) (95% CI)
- Age 60-74 years vs 15-59 years, AC failure
- HR 0.63 (0.44 to 0.89) (95% CI)
- Age 75 + years vs 15-59 years, AC failure
- HR 0.36 (0.20, 0.64) (95% CI)
Secondary outcomes
Suspected catheter associated bloodstream infection (CABSI)
- Most common failure type
- 11%
- Incidence rate per 1000 catheter days
- 15.3
- Abnormal insertion site appearance
- SHR 2.71 (1.48, 4.99) (95% CI)
Occlusion
- Occlusion
- 8%
- Incidence rate per 1,000 catheter days
- 11.9
- Ultrasound-assisted insertion
- sub-HR 0.11 (0.03, 0.43) (95% CI)
- Females
- adjusted sub-HR 2.53 (1.49, 4.29) (95% CI)
- Diabetes
- SHR 0.15 (0.04, 0.63) (95% CI)
Accidental removal
- Accidental removal
- 4%
- Incidence rate per 1000 catheter days
- 5.5
CABSI
- CABSI
- 16 (2%)
Original publication
Risk factors for arterial catheter failure and complications during critical care hospitalisation: a secondary analysis of a multisite, randomised trial. J Intensive Care. Published 8 March 2024. doi:10. 1186/ s40560-024-00719-1
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