Cardiothoracic & vascular anesthesia
Risk Factors for Postoperative Pulmonary Complications Leading to Increased Morbidity and Mortality in Patients Undergoing Thoracic Surgery for Pleural Empyema
Authors' conclusion
The incidence of PPCs is a significant risk factor for morbidity and mortality after surgery for pleural empyema.
Study context
- Population
- Adults undergoing thoracic surgery for pleural empyema, single large university hospital, January 2017–December 2021
- Participants
- 250 adults
- Exposure
- Video-assisted thoracoscopic surgery vs open thoracotomy
- Video-assisted thoracoscopic surgeryn = 122
- Open thoracotomyn = 128
- Outcome
- Incidence of ≥1 PPCs and independent risk factors for PPCs
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Odds ratio (95% CI)
Preoperative respiratory failure
5.8(2.4–13.1)
GA without regional analgesia techniques
2.9(1.4–5.8)
Open thoracotomy and subsequent resurgery
3.9(1.5–9.9)
Surgery outside regular working hours
3.1(1.2–8.2)
Postoperative sepsis
2.6(1.1–6.8)
- Patients with ≥1 postoperative pulmonary complications (PPCs)
- 42% [105]
Observational data: associations, not effects.
Further findings
PPCs as independent factors for unplanned ICU admission and death
| OR (95% CI) | ||
|---|---|---|
| >1 PPCUnplanned ICU admission | 10.5 (2.1–51) | |
| ≥2 PPCsDeath within 360 days | 4.5 (2.2–12.3) | |
| ≥1 PPCsDeath within 30 days | 1.2 (1.1–1.3) | |
| 0.050.21520Odds ratio (log scale) |
Resurgery and unexpected ICU re-admission
- Resurgery
- 28% (n = 70)
- Unexpected ICU re-admission
- 10% (n = 25)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Risk Factors for Postoperative Pulmonary Complications Leading to Increased Morbidity and Mortality in Patients Undergoing Thoracic Surgery for Pleural Empyema. J Cardiothorac Vasc Anesth. Published 20 April 2023. doi:10.
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