Organ support & nutrition

A consensus of international experts on definition, sampling, treatment, and prevention of peripheral extracorporeal membrane oxygenation cannula-site infection obtained by the Delphi method: the SAVECMO study

Intensive Care MedPublished Delphi consensus study

Methodological details4 Delphi rounds, international expert panel, consensus ≥ 70% agreement
  • 4 Delphi rounds
  • International expert panel
  • Consensus ≥ 70% agreement

Recommendations

As issued by the authors

  1. Suspect ECMO cannula-site infections (ECMO-CSI) in clinical scenarios such as purulent discharge and local inflammatory signs

  2. Standardized sampling with swabs and purulent drainage aspiration recommended; other techniques rejected

  3. ECMO-CSI defined by pathogen isolation on local microbiological sampling plus purulent discharge or local inflammatory signs

  4. Prevention: chlorhexidine-impregnated or semipermeable polyurethane dressings, unchanged for 7 days unless soiled or bleeding

  5. Systematic antibiotic prophylaxis not recommended, even for surgical extracorporeal membrane oxygenation (ECMO)

Original publication

A consensus of international experts on definition, sampling, treatment, and prevention of peripheral extracorporeal membrane oxygenation cannula-site infection obtained by the Delphi method: the SAVECMO study. Intensive Care Med. Published 8 January 2026. doi:10.1007/s00134-025-08269-2

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