Cardiac arrest & resuscitation
Sedation, temperature and pressure after cardiac arrest and resuscitation—The STEPCARE trial: A statistical analysis plan
Study context
- Population
- Adults admitted to intensive care unit (ICU) comatose after resuscitation from OHCA
- Planned comparison
- Sedation, temperature and blood pressure strategies in three separate comparisons (SED-CARE, TEMP-CARE, MAP-CARE)
- Primary endpoint
- All-cause mortality
- Follow-up
- 6 months after randomization
Methodological detailsmulticenter, parallel-group, factorial, superiority, intention-to-treat, Analyses performed independently by two statisticians, Prognosticators, outcome assessors, statisticians, data managers, steering group and manuscript writers blinded to allocation
- Multicenter
- Parallel-group
- Factorial
- Superiority
- Intention-to-treat
- Analyses performed independently by two statisticians
- Prognosticators, outcome assessors, statisticians, data managers, steering group and manuscript writers blinded to allocation
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Sedation, temperature and pressure after cardiac arrest and resuscitation—The STEPCARE trial: A statistical analysis plan. Acta Anaesthesiol Scand. Published 10 April 2025. doi:10.
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