Sepsis-induced myocardial dysfunction diagnosed with strain versus non-strain echocardiography parameters: incidence, evolution and association with prognosis
Authors' conclusion
The incidence of SIMD in septic shock is higher when using STE criteria, with lower reversibility in the first week. A broad definition of SIMD utilizing STE criteria does not seem to provide additional prognostic value.
Study context
- Population
- Septic shock patients admitted to intensive care
- Participants
- 98 consecutive patients
- Exposure
- Speckle tracking echocardiography (STE) vs non-STE echocardiographic criteria for diagnosing sepsis-induced myocardial dysfunction (SIMD)
- Outcome
- Prevalence of SIMD (any left ventricular (LV) systolic and/or diastolic and/or right ventricular (RV) systolic dysfunction)
- Follow-up
- Day 1
Methodological detailssingle-centre, consecutive patients
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
SIMD
P = 0.072
Observational data: associations, not effects.
Further findings
LV diastolic dysfunction · day 1
P = 1.00
LV systolic dysfunction · day 1
P = 0.115
RV systolic dysfunction · day 1
P = 0.096
Recovery from SIMD · day 7
P = 0.033
Recovery from SIMD · day 30
P = 0.501
30-day mortality and its association with SIMD
- 30-day mortality
- 33/98, 33.7%
- Associated with SIMD by non-STE
- P = 0.010
- Not associated with SIMD by STE
- P = 0.057
- Cox regression: only LVDD by non-STE criteria predicted 30-day mortality
- P = 0.005
Original publication
Sepsis-induced myocardial dysfunction diagnosed with strain versus non-strain echocardiography parameters: incidence, evolution and association with prognosis. Ann Intensive Care. Published 25 September 2025. doi:10.
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