Cardiothoracic & vascular anesthesia
Serratus plane block versus standard of care for pain control after totally endoscopic aortic valve replacement: a double-blind, randomized controlled, superiority trial
Authors' conclusion
Combined deep and superficial single-injection serratus anterior plane block is superior to standard of care in reducing opioid requirements and postoperative pain intensity up to 24 hours after totally endoscopic aortic valve replacement.
Study context
- Population
- Patients undergoing totally endoscopic aortic valve replacementanalysed
- Participants
- 75 patients
- Comparison
- Serratus anterior plane vs Control
- Serratus anterior planen = 38
- Controln = 37reference
- Primary endpoint
- Piritramide consumption
- Follow-up
- First 24 hours after serratus anterior plane block placement
Methodological detailsprospective, double-blinded, superiority
- Prospective
- Double-blinded
- Superiority
Primary result
As reported in the abstract
24-hour cumulative opioid use (MME) · up to 24 hours
P < 0.01
Further findings
Pain scores · 4, 8 and 24 hours
- Lower in the intervention arm at 4, 8 and 24 hours
Original publication
Serratus plane block versus standard of care for pain control after totally endoscopic aortic valve replacement: a double-blind, randomized controlled, superiority trial. Reg Anesth Pain Med. Published 18 August 2023. doi:10.
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