Severity of Inhalation Injury and Risk of Nosocomial Pneumonia: A Retrospective Cohort Study
Authors' conclusion
In this study, among patients with inhalation injury, more severe injury was associated with higher hazard of NP in competing risk analysis.
Study context
- Population
- Patients with suspected inhalation injury admitted to a regional burn center 2011–2022 who underwent diagnostic bronchoscopy within 48 h of admission236 hospitalized ≥ 48 h
- Participants
- 245 patients
- Exposure
- High-grade vs low-grade inhalation injury
- High-graden = 51
- Low-graden = 180reference
- No inhalation injuryn = 14
- Outcome
- Nosocomial pneumonia (NP), with death and hospital discharge as competing risks
Methodological detailssingle regional burn centre, competing risk analysis
- Single regional burn centre
- Competing risk analysis
Main finding
As reported in the abstract
NP (patients hospitalized ≥ 48 h)
High-grade vs Low-gradeEstimate (95% CI)P value
Proportional cause-specific hazard model
cause-specific HR 2.04(1.26–3.30)
P = 0.004Fine-Gray subdistribution hazard model
subdistribution HR 2.24(1.38–3.64)
P = 0.001Observational data: associations, not effects.
Original publication
Severity of Inhalation Injury and Risk of Nosocomial Pneumonia: A Retrospective Cohort Study. Chest. Published 2 July 2024. doi:10.
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