Pediatric anesthesia & critical care
Sevoflurane Washin With the Dräger Apollo and GE Datex Ohmeda Aisys Workstations in Healthy Children
Authors' conclusion
The washing of sevoflurane with the Dräger Apollo workstation is slower, and the maximum sevoflurane concentrations are less in children than with the Ohmeda Aisys workstation.
Study context
- Population
- Healthy children scheduled for elective surgery undergoing inhalational induction with 8% sevoflurane and 66% nitrous oxide12 per workstation
- Participants
- 24 children
- Exposure
- Apollo vs Aisys
- Apollon = 12
- Aisysn = 12reference
- Outcome
- Sevoflurane wash-in profiles (derived wash-in metrics during induction)
Main finding
As reported in the abstract
- Mean inspired sevoflurane concentrations lower with Apollo vs Aisys
- p < 0.013
Observational data: associations, not effects.
Secondary outcomes
| Outcome | Apollo | Aisys | Estimate | P value | |
|---|---|---|---|---|---|
| Inspired sevoflurane concentration · 1 min22% less with Apollo · mean | 6.4% (SD 0.4%) | 7.8% (SD 0.67%) | mean difference 1.4 (95% CI 0.88–1.8) | P < 0.0001 | |
| Maximum inspired sevoflurane concentration during induction18% less with Apollo · mean | 7.2% (SD 0.3%) | 8.5% (SD 0.4%) | mean difference 1.3 (95% CI 0.99–1.6) | P < 0.0001 | |
| Maximum expired sevoflurane concentration during induction15% less with Apollo · mean | 6.8% (SD 0.37%) | 7.8% (SD 0.9%) | mean difference 1.01 (95% CI 0.41–1.6) | P < 0.002 | |
| Time to reach 90% of maximum inspired concentration during induction3.5-fold greater with Apollo · median, min | 1.75 (IQR 1–2.4) | 0.5 (IQR 0.5–0.5) | median difference −1.25 (95% CI −1.5 to −0.5) | P < 0.0019 | |
| −2−1012Difference (linear scale) |
Original publication
Sevoflurane Washin With the Dräger Apollo and GE Datex Ohmeda Aisys Workstations in Healthy Children. Paediatr Anaesth. Published 3 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →