Short- and long-term outcomes and 15-year time trends of kidney replacement therapy in critically ill patients with obesity: an observational cohort
Authors' conclusion
Among critically ill obese patients, KRT was independently associated with increased 90-day mortality.
Study context
- Population
- Critically ill patients with obesity (BMI ≥ 30 kg/m²) admitted to a medico-surgical ICU, 2009–2024
- Participants
- 2,192 patients
- Exposure
- Kidney replacement therapy (KRT) vs no KRT
- KRTn = 295
- Outcome
- Mortality (Kaplan-Meier curves and multivariate Cox analysis)
- Follow-up
- 90 days
Methodological detailssingle-centre medico-surgical ICU, consecutive patients
- Single-centre medico-surgical ICU
- Consecutive patients
Main finding
As reported in the abstract
P < 0.0001
Observational data: associations, not effects.
Secondary outcomes
Acute kidney injury (AKI) incidence time trend over 15 years
- AKI incidence decreased
- P < 0.001
Original publication
Short- and long-term outcomes and 15-year time trends of kidney replacement therapy in critically ill patients with obesity: an observational cohort. Intensive Care Med. Published 30 June 2025. doi:10.
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