A simplified standardized ultrasound-guided plane block for the Intercostobrachial nerve: Effective volume of 0.5 % ropivacaine determined by Dixon's up-and-down method
Authors' conclusion
This simplified standardized ultrasound-guided plane block can provide a reliable anesthesia of the intercostobrachial nerve, with an EV50 of 3.31 mL and an EV95 of 3.94 mL for 0.5 % ropivacaine.
Study context
- Population
- Patients undergoing upper limb surgery receiving a simplified US-guided intercostobrachial nerve (ICBN) plane block (needle target 3 cm caudal to the centre of the axillary artery on the anterior surface of the conjoint tendon)
- Participants
- 28 patients
- Outcome
- EV50 and EV95 of 0.5 % ropivacaine for the simplified ICBN plane block
Methodological detailsDixon's up-and-down method, probit regression, bootstrap analysis with 1000 resamples, Initial volume 5 mL; successful or failed block produced a 0.5 mL decrement or increment
- Dixon's up-and-down method
- Probit regression
- Bootstrap analysis with 1000 resamples
- Initial volume 5 mL; successful or failed block produced a 0.5 mL decrement or increment
Main finding
As reported in the abstract
Effective volume of 0.5 % ropivacaine
- Effective volume (EV50) (Dixon's up-and-down method), mean ± SD, mL
- 3.29 ± 0.60
- EV50 (probit regression), mL
- 3.31 (95% CI 3.09-3.53)
- Effective volume (EV95) (probit regression), mL
- 3.94 (95% CI 3.46-4.42)
- EV50 (bootstrap), mL
- 3.32 (95% CI 3.05-3.52)
- EV95 (bootstrap), mL
- 3.90 (95% CI 3.54-4.41)
Safety
- No adverse events occurred
Original publication
A simplified standardized ultrasound-guided plane block for the Intercostobrachial nerve: Effective volume of 0.5 % ropivacaine determined by Dixon's up-and-down method. J Clin Anesth. Published 29 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →