Regional anesthesia

Single injection combined suprascapular and axillary nerve block: A randomised controlled non‐inferiority trial in healthy volunteers

Acta Anaesthesiol ScandPublished Randomised controlled trial

Primary resultResult — go to the resultRatio of event rates 1.15 95% CI 0.88–1.51

Authors' conclusion

For our primary outcome, the 95% CI of the difference of event ratio included the non-inferiority margin. We are therefore unable to conclude that 5 ml LA is non-inferior to 20 ml LA with respect to block success rate.

Study context

Population
Healthy volunteers
Participants
16 vs 16
Comparison
5 ml vs 20 ml
  • 5 mln = 16
  • 20 mln = 16reference
Primary endpoint
Successful shoulder block (cutaneous sensory affection of the axillary nerve and motor affection of the suprascapular nerve, >50% reduction in external rotation force by dynamometry)
Methodological detailsnon-inferiority, healthy volunteers, ultrasound guided
  • Non-inferiority
  • Healthy volunteers
  • Ultrasound guided

Primary result

As reported in the abstract

Ratio of event rates

1.15

95% CI 0.88–1.51

Events by treatment group

Secondary outcomes

Change in lung function (spirometry)

All mean reductions in lung function parameters non-significantly lower in the 5 ml group vs the 20 ml group

Original publication

Single injection combined suprascapular and axillary nerve block: A randomised controlled non‐inferiority trial in healthy volunteers. Acta Anaesthesiol Scand. Published 1 October 2022. doi:10.1111/aas.14147

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