Social determinants of health and sepsis: a case-control study
Authors' conclusion
Despite no association between the SDoH variables available and sepsis, we found a higher rate of sepsis cases and sepsis deaths among individuals living in systematically disadvantaged neighbourhoods.
Study context
- Population
- Randomly selected adults admitted to the ED of a large academic tertiary care hospital in Hamilton, ON, Canada
- Participants
- 300 participants
- Comparison
- Patients with sepsis vs without sepsis
- Sepsisn = 100
- Without sepsisn = 200reference
- Outcome
- Association of SDoH (neighbourhood household income, smoking history, social support, history of alcohol disorder) with development of sepsis
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Association of SDoH with sepsis
- In patients with social determinants of health (SDoH) available in records, no SDoH significantly associated with sepsis
- Factors significantly associated with sepsis: arrival by ambulance, absence of a family physician, higher Hamilton Early Warning Score, recorded history of dyslipidemia
- Multivariate logistic regression
Observational data: associations, not effects.
Further findings
Age
Sepsis cases and sepsis deaths in systematically disadvantaged neighbourhoods
- Rate approximately two times higher among patients living in systematically disadvantaged neighbourhoods, compared with their proportion of the Hamilton population
Availability of SDoH data
- Individual or household income and race not available in the medical chart
Original publication
Social determinants of health and sepsis: a case-control study. Can J Anaesth. Published 2 July 2024. doi:10.
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