Respiratory failure & ventilation

Socioeconomic status and ECMO outcomes in severe ARDS

Ann Intensive CarePublished Retrospective cohort study

Authors' conclusion

Severe ARDS requiring ECMO disproportionately affected patients from socioeconomically deprived areas, irrespective of etiology. However, deprivation was not linked to worse outcomes.

Study context

Population
Adults receiving ECMO for acute respiratory failure (severe ARDS), France, March 2015 to December 2021
Participants
1,722 adults
Exposure
COVID-19 ARDS vs ARDS due to influenza or other causes, on ECMO
  • COVID-19n = 1,245
  • Influenzan = 107reference
  • Other causesn = 370
Outcome
Residence in most deprived neighborhoods
Methodological detailsnationwide French healthcare database
  • Nationwide French healthcare database

Main finding

As reported in the abstract

Overall in most deprived neighborhoods
27%
Overrepresentation vs less deprived neighborhoods
P = 0.039

Observational data: associations, not effects.

Further findings

OutcomeCOVID-19InfluenzaOther causesOR (95% CI)
In-hospital mortalityOther causes vs Influenza · adjusted56%48%60%1.70 (1.03–2.81)
OutcomeCOVID-19InfluenzaOther causes
ICU LOS in survivorsmedian 56 (IQR 36–78) days— not stated in the abstract— not stated in the abstract

— not stated in the abstract

In-hospital mortality — Difference across etiologies
p = 0.080

ICU LOS in survivors

Longest in COVID-19 survivors, who also required longer ECMO support

Independent predictors of in-hospital death

Older age and RRT at ECMO initiation; socioeconomic deprivation not associated with outcomes

Safety

More complications in COVID-19 survivors

Original publication

Socioeconomic status and ECMO outcomes in severe ARDS. Ann Intensive Care. Published 16 January 2026. doi:10.1016/j.aicoj.2025.100012

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