Spontaneous diuresis in combination with furosemide stress test (SD-FST) as predictor for successful liberation from kidney replacement therapy: a prospective observational study
Authors' conclusion
In critically ill patients with recovery of SD > 400ml/d during ongoing KRT, the FST helps to identify patients who can be successfully liberated from KRT.
Study context
- Population
- Critically ill patients on kidney replacement therapy (KRT) for acute kidney injury (AKI) with spontaneous diuresis ≥400 ml in 24 h without diuretics98 evaluated
- Participants
- 100 patients
- Exposure
- Furosemide stress test (FST)-positive vs FST-negative
- FST-positiven = 76
- FST-negativen = 22reference
- Outcome
- Need to restart KRT
- Follow-up
- 7 days
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Resumption of KRT
P < 0.001
Observational data: associations, not effects.
Further findings
Urine output after FST predicting successful release from KRT
- AUC (p < 0.001)
- 0.87
Original publication
Spontaneous diuresis in combination with furosemide stress test (SD-FST) as predictor for successful liberation from kidney replacement therapy: a prospective observational study. Crit Care. Published 26 May 2025. doi:10.
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