Cardiothoracic & vascular anaesthesia
Statin therapy after elective abdominal aortic aneurysm repair improves long-term survival
Main finding · Long-term survival, postoperative statin use vs no statin use during follow-upResult — go to the resultHazard ratio (long-term survival) 1.43 95% CI 1.34–1.54Authors' conclusion
In this nationwide propensity score matched cohort study, preoperative statin treatment had no benefit regarding 90-day perioperative survival, but postoperative statin treatment markedly improved long-term survival.
Study context
- Population
- Patients undergoing elective abdominal aortic aneurysm repair, Swedish nationwide registers, 2006 to 2018three propensity score matched cohorts
- Exposure
- Statin use vs no statin use; high-intensity vs low-moderate-intensity statin therapy
- Outcome
- Long-term survival, postoperative statin use vs no statin use during follow-up
- Follow-up
- Long-term
Methodological detailspropensity score matched, nationwide registers
- Propensity score matched
- Nationwide registers
Main finding
As reported in the abstract
Hazard ratio (long-term survival)
1.43
95% CI 1.34–1.54
Postoperative statin users vs Non-users
HR (long-term survival) 1.43 (95% CI 1.34–1.54)
Observational data: associations, not effects.
Further findings
| Outcome | HR (long-term survival) (95% CI) | |
|---|---|---|
| Long-term survival, high-intensity vs low-medium-intensity statin therapy · long-term follow-upNo advantage of high-intensity therapy · propensity score matched cohort | 1.00 (0.80–1.25) | |
| 0.512Hazard ratio (long-term survival) (log scale) |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Statin therapy after elective abdominal aortic aneurysm repair improves long-term survival. Br J Surg. Published 10 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →