Cardiothoracic & vascular anesthesia
Sternotomy Wound Infiltration With Liposomal Versus Plain Bupivacaine for Postoperative Analgesia After Elective Cardiac Surgery
Authors' conclusion
LB added to PB for sternotomy wound infiltration during elective cardiac surgery did not significantly improve the quality of postoperative analgesia.
Study context
- Population
- Adults undergoing elective cardiac surgery through median sternotomy, tertiary care university hospitalcompleted the study for analysis
- Participants
- 60 adults
- Comparison
- Wound infiltration with liposomal bupivacaine (LB) plus plain bupivacaine (PB) vs PB alone
- LBn = 29
- PBn = 31reference
- Primary endpoint
- Pain scores
- Follow-up
- 72 hours
Methodological detailsprospective, double-blinded, single institution
- Prospective
- Double-blinded
- Single institution
Primary result
As reported in the abstract
4 to 72 hours
- Trend of mean pain scores at movement (mixed-model regression) significantly lower in LB vs PB
- p = 0.01
Further findings
Opioid consumption (oral morphine equivalents) · 72 hours · not significantly different
P = 0.29
Recovery characteristics
- Comparable between groups
Safety
Adverse events
- Comparable between groups
Original publication
Sternotomy Wound Infiltration With Liposomal Versus Plain Bupivacaine for Postoperative Analgesia After Elective Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 12 October 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →