Respiratory failure & ventilation
Stroke volume variation induced by lung recruitment maneuver to predict fluid responsiveness in patients receiving mechanical ventilation: A systematic review and meta-analysis
Authors' conclusion
Based on the currently available evidence, ΔSVLRM has a good diagnostic value for predicting the fluid responsiveness in adult patients undergoing mechanical ventilation.
Study context
- Population
- Mechanically ventilated adult patients
- Participants
- 256 participants · 6 studies
- Outcome
- Accuracy of ΔSVLRM in predicting fluid responsiveness
Methodological detailsQUADAS-2 quality assessment, Risk of bias and applicability concerns low; no significant publication bias
- QUADAS-2 quality assessment
- Risk of bias and applicability concerns low; no significant publication bias
Pooled result
As reported in the abstract
Accuracy of ΔSVLRM for predicting fluid responsiveness (pooled)
- Pooled sensitivity
- 0.84 (95% CI 0.77-0.90)
- Pooled specificity
- 0.79 (95% CI 0.70-0.86)
- Diagnostic odds ratio (DOR)
- 22.15 (95% CI 7.62-64.34)
- AUC
- 0.90 (95% CI 0.87-0.92)
- Positive diagnostic likelihood ratio (DLR)
- 4.53 (95% CI 2.50-8.18)
- Negative DLR
- 0.19 (95% CI 0.11-0.35)
- Post-test probability, positive test (pre-test probability 52%)
- 83%
- Post-test probability, negative test (pre-test probability 52%)
- 17%
Original publication
Stroke volume variation induced by lung recruitment maneuver to predict fluid responsiveness in patients receiving mechanical ventilation: A systematic review and meta-analysis. J Clin Anesth. Published 5 July 2024. doi:10.
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