Respiratory failure & ventilation
Superiority of Lateral Decubitus Strategy in Preventing Atelectasis From Obscuring Targets During Robotic Bronchoscopy: Lateral Decubitus Strategy vs Ventilatory Strategy to Prevent Atelectasis Trial
Authors' conclusion
Our results suggest that LADS is superior to VESPA in preventing atelectasis from obscuring targets in patients with nodules located in dependent areas, can help eliminate atelectasis, is safe, and is also associated with better procedural outcomes such as TIL and diagnostic yield.
Study context
- Population
- Patients undergoing robotic bronchoscopy for nodules ≤ 3 cm in dependent lung zonesanalysed
- Participants
- 62 patients
- Comparison
- Lateral decubitus strategy (LADS) vs ventilatory strategy to prevent atelectasis (VESPA)
- LADSn = 29
- VESPAn = 33reference
- Primary endpoint
- Atelectasis obscuring the target detected with mobile cone-beam CT
Methodological details1:1, crossover of patients with atelectasis obscuring target
- 1:1
- Crossover of patients with atelectasis obscuring target
Primary result
As reported in the abstract
LADS
0
events
VESPA
27.3%
9 of 33
P = 0.002
Secondary outcomes
| Outcome | LADS | VESPA | P value |
|---|---|---|---|
| Tool in lesion (TIL) | 100% (95% CI 88.1%–100%) | 72.7% (95% CI 54.5%–86.7%) | P = 0.005 |
| Diagnostic yield on index biopsy | 86.2% (95% CI 68.3%–96.1%) | 57.6% (95% CI 39.2%–74.5%) | P = 0.026 |
Crossover from VESPA to LADS
- Atelectasis eliminated leading to tool in lesion (TIL) in all crossed-over patients
- 9
- Diagnosis obtained after crossover
- 7 (78%)
Safety
- Major complications
- 0
- No differences in rate of minor complications
Original publication
Superiority of Lateral Decubitus Strategy in Preventing Atelectasis From Obscuring Targets During Robotic Bronchoscopy: Lateral Decubitus Strategy vs Ventilatory Strategy to Prevent Atelectasis Trial. Chest. Published 8 January 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →