Surgical rectus sheath block versus laparoscopic bilateral dual transversus abdominis plane block after minimally invasive colorectal cancer surgery: randomized clinical trial of impact on recovery
Authors' conclusion
BD-TAP block resulted in better 24-h recovery than IV-PCA alone. Superiority of SRSB was not demonstrated.
Study context
- Population
- Adults undergoing minimally invasive colorectal resection at a Japanese cancer centre309 analysed
- Participants
- 320 adults
- Comparison
- Surgical rectus sheath block (SRSB) or laparoscopic bilateral dual transversus abdominis plane (BD-TAP) block added to intravenous patient-controlled analgesia (IV-PCA) vs IV-PCA alone
- Controln = 110reference
- SRSBn = 107
- BD-TAP blockn = 103
- Primary endpoint
- Questionnaire (QoR-15) score (Japanese version) after arrival in the PACU
- Follow-up
- 24 h
Methodological detailssingle-centre, three-arm, superiority, stratified block allocation, patient- and outcome assessor-blinded, Between July 2024 and December 2025
- Single-centre
- Three-arm
- Superiority
- Stratified block allocation
- Patient- and outcome assessor-blinded
- Between July 2024 and December 2025
Primary result
As reported in the abstract
24-h QoR-15 score
Each group vs controlAdjusted mean difference, points (95% CI)P value
BD-TAP block
10.44(3.06–17.83)
one-sided P = 0.003SRSBsuperiority not demonstrated
5.50(−1.88 to 12.89)
one-sided P = 0.072Secondary outcomes
| Outcome | Adjusted mean difference (points) (95% CI) | P value | |
|---|---|---|---|
| 48-h QoR-15 scoreBD-TAP block vs control · exploratory finding unadjusted for multiplicity | 8.01 (0.18–15.83) | two-sided P = 0.045 | |
| −1001020Difference, points (linear scale) |
Time to first rescue analgesia
Time to first rescue analgesia
- Longer with SRSB and BD-TAP block than control
Cumulative 48-h fentanyl consumption and hospital LOS
- Did not differ significantly
Safety
- No block-related complications observed
Original publication
Surgical rectus sheath block versus laparoscopic bilateral dual transversus abdominis plane block after minimally invasive colorectal cancer surgery: randomized clinical trial of impact on recovery. Br J Surg. Published 2 September 2026. doi:10.
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