Safety, quality & education

Systematic Review of Surgical Site Infection Prevention Guideline Recommendations for Maintenance of Homeostasis in the Perioperative Period

AnesthesiologyPublished Systematic review of guidelines

Authors' conclusion

There was broad consensus regarding the importance of optimizing intraoperative homeostasis to reduce infections. However, there was substantial heterogeneity in both the studies cited and the specific recommendations provided regarding maintenance of oxygenation, normovolemia, normothermia and glycemic targets.

Study context

Population
Surgical site infection prevention guidelines published in the past 10 yr
Participants
8 guidelines
Outcome
Current recommendations for maintenance of homeostasis in surgical site infection prevention guidelines

Pooled result

As reported in the abstract

  • Broad consensus on the importance of optimizing intraoperative homeostasis to reduce infections
  • Substantial heterogeneity in studies cited and specific recommendations on oxygenation, normovolemia, normothermia and glycemic targets

Original publication

Systematic Review of Surgical Site Infection Prevention Guideline Recommendations for Maintenance of Homeostasis in the Perioperative Period. Anesthesiology. Published 13 May 2025. doi:10.1097/aln.0000000000005438

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