Respiratory failure & ventilation
Systolic Function of the Left Ventricle Assessed by Speckle Tracking in Cardiovascularly Healthy Subjects Is Not Affected by the Initiation of Mechanical Ventilation: Comparison With Conventional Echocardiographic Methods
Authors' conclusion
The initiation of mechanical ventilation in cardiovascularly healthy patients does not significantly alter global left ventricular systolic function, as assessed by speckle tracking.
Study context
- Population
- Cardiovascularly healthy patients undergoing scheduled surgery under GA, university hospital
- Participants
- 20 patients
- Exposure
- Before vs after initiation of mechanical ventilation
- Outcome
- GLS and its six apical four-chamber segments
Methodological detailsbefore-after comparison
- Before-after comparison
Main finding
As reported in the abstract
- No significant differences in global longitudinal strain (GLS) after initiation of mechanical ventilation
- No significant changes in the six individual segments of GLS
Observational data: associations, not effects.
Further findings
LV ejection fraction, LV outflow tract velocity-time integral, E/e' ratio
- No significant differences after initiation of mechanical ventilation
Mitral annular plane systolic excursion (MAPSE) and lateral S' wave velocity
- Significant differences after initiation of mechanical ventilation; all values remained within normal range
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Systolic Function of the Left Ventricle Assessed by Speckle Tracking in Cardiovascularly Healthy Subjects Is Not Affected by the Initiation of Mechanical Ventilation: Comparison With Conventional Echocardiographic Methods. J Cardiothorac Vasc Anesth. Published 26 February 2026. doi:10. 1053/ j. jvca. 2026. 02. 033
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