Respiratory failure & ventilation

Using automatic speckle tracking imaging to measure diaphragm excursion and predict the outcome of mechanical ventilation weaning

Crit CarePublished Diagnostic accuracy study

Authors' conclusion

Automatic speckle tracking analysis of the diaphragm showed high consistency with conventional manual ultrasound measures. Diaphragmatic excursion and its excursion velocity helped predict mechanical ventilation weaning failure, prolonged weaning, as well as in-hospital adverse outcomes.

Study context

Population
Critically ill mechanically ventilated subjects undergoing speckle-tracking ultrasonography of the right/left hemidiaphragm before the SBT88 completed follow-up
Participants
160 participants
Comparison
Mean excursion vs Diaphragmatic velocity
Outcome
Predictive value of automatic speckle tracking diaphragm excursion for weaning outcome
Methodological detailsprospective, multicentre, observational, pilot
  • Prospective
  • Multicentre
  • Observational
  • Pilot

Performance

As reported in the abstract

Weaning failure
Test or modelArea under the ROC curve (AUROC)
Excursion0.659

Excursion

Area under the ROC curve (AUROC)0.659

Further findings

OutcomeValues
Correlation of automatic vs manual measurementExcursion R 0.69 · Velocity R 0.65
Prolonged weaningExcursion AUROC 0.824 · Velocity AUROC 0.786
In-hospital death/withdrawal of treatmentExcursion AUROC 0.653

Incidence of weaning failure

Overall incidence of weaning failure
43.18%

Correlation of automatic vs manual measurement

Significant correlation between automatic and manual measurement

Prolonged weaning

High diagnostic values for prolonged weaning

In-hospital death/withdrawal of treatment

Moderate diagnostic value

Original publication

Using automatic speckle tracking imaging to measure diaphragm excursion and predict the outcome of mechanical ventilation weaning. Crit Care. Published 14 January 2023. doi:10.1186/s13054-022-04288-3

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