Neuroanesthesia & neurocritical care
Temporal trends in mortality and provision of intensive care in younger women and men with acute myocardial infarction or stroke
Authors' conclusion
Sex and gender disparities in disease management and outcomes persist in the era of modern interventional neurology and cardiology with opposite trends observed in younger stroke and AMI patients admitted to intensive care.
Study context
- Population
- Younger patients aged 18 to ≤ 52 years with acute myocardial infarction (AMI) or acute stroke admitted to Swiss intensive care unit (ICUs), 01/2008–12/2019
- Participants
- 16,954 patients
- Exposure
- Women vs Men
- Outcome
- Sex-specific temporal trends in ICU admission and ICU mortality
- Follow-up
- 12 years
Methodological detailstemporal trend analysis, national (Swiss ICUs)
- Temporal trend analysis
- National (Swiss ICUs)
Main finding
As reported in the abstract
Sex-specific temporal trends in ICU admission and ICU mortality, AMI and stroke · 2008–2019
Women
- 6.4%
Men
- 4.5%
Odds ratio (CI)P value
Women vs MenAMI ICU mortality trend; significantly increased
1.2(1.10–1.30)
P = 0.032MenAMI ICU mortality trend; unchanged
0.99(0.94–1.03)
P = 0.71Women vs MenStroke ICU mortality trend; tended to decrease
0.91(0.85–0.95)
P = 0.057MenStroke ICU mortality trend; essentially unaltered
0.99(0.94–1.03)
P = 0.75- Stroke ICU admission rates increased per year in both sexes
- between 3.6 and 4.1%
Observational data: associations, not effects.
Further findings
| Outcome | Women | Men |
|---|---|---|
| Stroke: ICU admissions and ICU mortality | ||
| ICU mortality trend OR | 0.91 [0.85-0.95, p = 0.057] | 0.99 [0.94-1.03], p = 0.75 |
- Stroke: ICU admissions and ICU mortality — ICU admission rates increased 3.6 to 4.1% per year in both sexes
- 3.6 and 4.1%
Stroke: ICU admissions and ICU mortality
- ICU mortality tended to decrease only in women; essentially unaltered in men
Interventions
- Tissue perfusion-restoring interventions more often in men with AMI; no sex difference in neurovascular interventions
Original publication
Temporal trends in mortality and provision of intensive care in younger women and men with acute myocardial infarction or stroke. Crit Care. Published 12 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →