Cardiothoracic & vascular anesthesia
The Association of Preoperative Cognitive Dysfunction to Common Intraoperative Electroencephalographic Parameters and Cerebral Hypoxia During Cardiac Surgery
Primary result · Burst suppression duration (BSD)Result — go to the resultCohen's d 0.33Authors' conclusion
Preoperative cognitive dysfunction was associated with significantly lower SEFs, indicating increased isoflurane sensitivity without affecting BS or correlating with CO.
Study context
- Population
- Patients ≥60 years undergoing CABG and/or valve surgery under general (inhalational) anesthesia at a single academic center
- Participants
- 110 patients
- Comparison
- Preoperative cognitive impairment vs normal cognition
Methodological detailstriple-blinded, multicentre trial, single-centre cohort
- Triple-blinded
- Multicentre trial
- Single-centre cohort
Primary result
Burst suppression duration (BSD)
Cohen's d
0.33
P = 0.09
As reported in the abstract
Further findings
Time in cerebral desaturation (CO <60%) · spread kind not named in abstract
P = 0.6
| Outcome | Difference (lower SEF) (Hz) (95% CI) | P value |
|---|---|---|
| Spectral edge frequency (SEF), adjustedAdjusted analyses | 1.4 (0.07–2.6) | P = 0.03 |
Concurrent and nonconcurrent abnormal EEG and cerebral oximetry (CO) values
- No disparities between the groups
Original publication
The Association of Preoperative Cognitive Dysfunction to Common Intraoperative Electroencephalographic Parameters and Cerebral Hypoxia During Cardiac Surgery. Anesth Analg. Published 14 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →