Perioperative medicine & outcomes
The burden of pre-operative anaemia and postoperative outcomes in 15 166 surgical patients from a public hospital in Brazil: A retrospective cohort study
Main finding · In-hospital 30-day postoperative mortalityResult — go to the resultRelative risk 1.69 95% CI 1.44–1.99Authors' conclusion
Four out of 10 patients had anaemia. These patients had an increased risk of adverse postoperative outcomes.
Study context
- Population
- Adults undergoing surgery 2015–2019 at an 860-bed quaternary university-affiliated teaching hospital in Southern Brazil
- Participants
- 15,166 adults
- Exposure
- Preoperative anaemia vs no anaemia
- Anaemian = 6,387
- Outcome
- In-hospital postoperative mortality
- Follow-up
- 30 days
Methodological detailssingle-centre
- Single-centre
Main finding
In-hospital 30-day postoperative mortality
Relative risk
1.69
95% CI 1.44–1.99
P < 0.001
Anaemia vs No anaemia
RR 1.69 (95% CI 1.44–1.99); P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | RR (95% CI) | P value | |
|---|---|---|---|
| In-hospital 30-day postoperative mortality by anaemia severity (WHO; subgroup) · 30 daysMild anaemia vs No anaemia | 1.38 (1.12–1.71) | P = 0.003 | |
| In-hospital 30-day postoperative mortality by anaemia severity (WHO; subgroup) · 30 daysModerate anaemia vs No anaemia | 1.73 (1.43–2.10) | P < 0.001 | |
| In-hospital 30-day postoperative mortality by anaemia severity (WHO; subgroup) · 30 daysSevere anaemia vs No anaemia | 2.43 (1.92–3.07) | P < 0.001 | |
| Transfusion | 4.44 (3.90–5.06) | P < 0.001 | |
| Postoperative ICU admission | 1.09 (1.04–1.16) | P = 0.001 | |
| 0.20.5125Relative risk (log scale) |
Prevalence of preoperative anaemia
- Anaemic among included patients
- 6387 (42.1%)
Original publication
The burden of pre-operative anaemia and postoperative outcomes in 15 166 surgical patients from a public hospital in Brazil: A retrospective cohort study. Eur J Anaesthesiol. Published 23 September 2024. doi:10.
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