The effect of excessive noise rejection, noise filtering and twitch threshold on mechanomyograph twitch measurements
Authors' conclusion
A noise management system for a laboratory-built mechanomyograph showed excellent agreement with the manual interpretation of twitch waveforms. Varying the noise filtering level and amplitude threshold had a substantial effect on train-of-four counts but a minimal effect on train-of-four ratios.
Study context
- Population
- Patients under GA with twitch waveforms collected by mechanomyograph4,371 twitch measurements
- Participants
- 29 participants
- Comparison
- Noise detection algorithm vs Manual detection
- Outcome
- Agreement of excessive noise detection algorithm with manual detection
Methodological detailslaboratory-built mechanomyograph
- Laboratory-built mechanomyograph
Main finding
As reported in the abstract
Cohen's kappa ("almost perfect" agreement)
0.82
Further findings
Effect of varying filtering level and amplitude threshold on TOF counts and ratios
- Maximum average difference in TOF count
- 0.8
- Negligible effect on TOF ratios
Original publication
The effect of excessive noise rejection, noise filtering and twitch threshold on mechanomyograph twitch measurements. Anaesth Crit Care Pain Med. Published 3 March 2026. doi:10.
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