Anesthetic drugs & techniques

The effect of raw EEG implementation for assessing depth of anaesthesia on patient quality of recovery: A multicentre, double-blind, randomised controlled trial

Eur J AnaesthesiolPublished Randomised controlled trial

Primary result · QoR-15 scoreResult — go to the resultMean difference −3.2 95% CI −8.8 to 2.5

Authors' conclusion

A short tutorial on the raw electroencephalogram and its addition intra-operatively was not able to improve quality of recovery or reduce propofol consumption in middle-aged, largely female patients.

Study context

Population
Adults undergoing in-hospital laparoscopies and their anaesthesia practitioners (≥2 years' experience), four tertiary centres in Switzerlandpairs randomised
Participants
232 adults
Comparison
Tutorial vs No tutorial
Primary endpoint
Quality of recovery measured with the QoR-15 score
Follow-up
First postoperative day
Methodological detailsmulticentre, double-blind, four tertiary centres in Switzerland, patients 78% female
  • Multicentre
  • Double-blind
  • Four tertiary centres in Switzerland
  • Patients 78% female

Primary result

QoR-15 score

Mean difference

−3.2

95% CI −8.8 to 2.5

P = 0.273

Tutorial vs No tutorial
mean difference −3.2 (95% CI −8.8 to 2.5); P = 0.273

As reported in the abstract

Secondary outcomes

OutcomeMean difference (mg kg −1 h −1) (95% CI)P value
Propofol consumption0.36 (−0.01 to 0.73)P = 0.055

Original publication

The effect of raw EEG implementation for assessing depth of anaesthesia on patient quality of recovery: A multicentre, double-blind, randomised controlled trial. Eur J Anaesthesiol. Published 30 October 2025. doi:10.1097/eja.0000000000002301

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