Cardiothoracic & vascular anesthesia
The haemodynamic effects of phenylephrine after cardiac surgery
Main finding · Haemodynamic effects of phenylephrineResult — go to the resultMedian Δcardiac output 0.25 L/minAuthors' conclusion
In haemodynamically stable patients after cardiac surgery, phenylephrine increased PVR and SVR, but did not change the PVR/SVR ratio. Phenylephrine increased biventricular filling pressures and left ventricular end-diastolic area. Consequently, CO increased as ejection fraction was maintained.
Study context
- Population
- Patients in steady state after low-risk cardiac surgery
- Participants
- 30 patients
- Comparison
- Baseline vs Phenylephrine
- Outcome
- Haemodynamic effects of phenylephrine
Main finding
As reported in the abstract
Median Δcardiac output
0.25 L/min
P = 0.012
By group
- Ratio of systemic to pulmonary artery resistances not significantly changed
- P = 0.59
Original publication
The haemodynamic effects of phenylephrine after cardiac surgery. Acta Anaesthesiol Scand. Published 25 April 2023. doi:10. 1111/ aas. 14256
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