Cardiothoracic & vascular anesthesia
Preoperative Vulnerability and Postoperative Recovery in Vasoplegia After Cardiac Surgery With Cardiopulmonary Bypass
Authors' conclusion
Vasoplegia after cardiopulmonary bypass was associated with preoperative nutritional/functional vulnerability, impaired ventricular function, prior percutaneous coronary intervention, aortic surgical exposure, and delayed early postoperative recovery after measured-risk balancing.
Study context
- Population
- Adults undergoing cardiac or thoracic aortic surgery with CPB, university hospital, January 2014–December 2024
- Participants
- 572 adults
- Exposure
- Vasoplegia vs no vasoplegia
- Vasoplegian = 101
- Outcome
- Vasoplegia
Methodological detailssingle-centre, propensity score overlap weighting, multivariable logistic regression
- Single-centre
- Propensity score overlap weighting
- Multivariable logistic regression
Main finding
As reported in the abstract
Vasoplegia
17.7%
101
Observational data: associations, not effects.
Further findings
Vasoplegia by number of nutritional/functional deficits (subgroup)
| Outcome | OR (95% CI) | |
|---|---|---|
| Prolonged mechanical ventilation ≥48 hoursPropensity score overlap weighting | 2.20 (1.35–3.59) | |
| Prolonged ICU stay ≥7 daysPropensity score overlap weighting | 2.08 (1.26–3.45) | |
| In-hospital mortalityPropensity score overlap weighting | 3.09 (1.02–9.32) | |
| Composite poor postoperative outcomePropensity score overlap weighting | 2.03 (1.26–3.29) | |
| 0.10.31310Odds ratio (log scale) |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Preoperative Vulnerability and Postoperative Recovery in Vasoplegia After Cardiac Surgery With Cardiopulmonary Bypass. J Cardiothorac Vasc Anesth. Published 4 July 2026. doi:10.
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