Cardiac arrest & resuscitation
The impact of blood pressure targets on venous return physiology during post cardiac arrest care
Authors' conclusion
In conclusion, a higher MAP target effectively increased the stressed intravascular volume to sustain a higher CO.
Study context
- Population
- Survivors of OHCA in intensive care
- Participants
- 730 survivors
- Comparison
- Higher vs lower BP target
- MAP63n = 362reference
- MAP77n = 368
- Primary endpoint
- Venous return physiological variables (Pmsa, VRdP, RVR, Eh) over time
- Follow-up
- From ICU admission over 36 h
Methodological detailsexploratory, post-hoc analysis
- Exploratory
- Post-hoc analysis
Primary result
As reported in the abstract
- Pmsa consistently higher in MAP77
- p < .03
- Progressively increasing VRdP in MAP77
- p < .0001
- Increased CO in MAP77
- p < .001
- Similar stroke volumes; higher heart rate in MAP77
- p < .001
- Resistance to venous return (RVR) higher in MAP77, gradually decreased in both groups
- p < .04
Original publication
The impact of blood pressure targets on venous return physiology during post cardiac arrest care. Acta Anaesthesiol Scand. Published 16 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →