Cardiothoracic & vascular anesthesia

The Index for Mortality Prediction After Cardiac Transplantation (IMPACT) Score: Does Sex Matter?

J Cardiothorac Vasc AnesthPublished External validation study

Authors' conclusion

The IMPACT score exhibited poor discrimination and calibration in the International Society for Heart and Lung Transplantation 2009-2019 cohort, overall and by sex. There was no difference in 1-year mortality between women and men.

Study context

Population
Adults (≥18 y) undergoing first-time single orthotopic heart transplantation, International Society for Heart and Lung Transplantation registry, 2009–2018
Comparison
IMPACT score performance in women vs men
Outcome
AUC of IMPACT score for 1-year mortality
Follow-up
1 year
Methodological detailsregistry-based, stratified by sex
  • Registry-based
  • Stratified by sex

Performance

As reported in the abstract

Women

0.58

95% CI 0.55–0.61

Men

0.59

95% CI 0.58–0.61

AUC, full sample
0.59 (95% CI 0.57-0.60)

Further findings

1-year mortality · no difference

P = 0.22

1-year mortality — 1-year mortality, overall cohort
9.4%

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

The IMPACT Score: Does Sex Matter? J Cardiothorac Vasc Anesth. Published 8 July 2024. doi:10.1053/j.jvca.2024.07.005

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.