Anesthetic drugs & techniques

“The peripheral perfusion index discriminates haemodynamic responses to induction of general anaesthesia”

J Clin Monit ComputPublished Observational study

Authors' conclusion

During induction of general anaesthesia changes in PPI discriminated between the degrees of reduction in blood pressure and algorithm derived cardiac stroke volume and -output.

Study context

Population
Mixed population of surgical patients undergoing induction of GA
Participants
107 participants
Exposure
Peripheral Perfusion Index (PPI) decrease vs PPI increase after induction of GA
  • PPI decreasedn = 38
  • PPI increasedn = 69reference
Outcome
Relative changes of SV, CO and MAP compared to relative changes of PPI
Follow-up
2 min after induction

Main finding

As reported in the abstract

MAP, SV and CO (% of baseline)
GroupValueStroke volume (SV)Cardiac output (CO)
PPI decreased57 (SD ± 14) % of baseline (mean arterial pressure (MAP))63(± 18)%55(± 18)%
PPI increased70 (SD ± 15) % of baseline (MAP)80(± 16)%68(± 17)%

Value

PPI decreased57 (SD ± 14) % of baseline (MAP)
PPI increased70 (SD ± 15) % of baseline (MAP)

Stroke volume (SV)

PPI decreased63(± 18)%
PPI increased80(± 16)%

Cardiac output (CO)

PPI decreased55(± 18)%
PPI increased68(± 17)%
  • PPI decreased vs PPI increased: P < 0,001 — all differences

Observational data: associations, not effects.

Further findings

Total cohort MAP, SV, CO (% of baseline) · after induction

%

MAP
65 (± 16)
SV
74 (± 18)
CO
63 (± 16)
  • Mean(± st.dev.)

Original publication

“The peripheral perfusion index discriminates haemodynamic responses to induction of general anaesthesia”. J Clin Monit Comput. Published 8 June 2023. doi:10.1007/s10877-023-01035-z

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.