“The peripheral perfusion index discriminates haemodynamic responses to induction of general anaesthesia”
Authors' conclusion
During induction of general anaesthesia changes in PPI discriminated between the degrees of reduction in blood pressure and algorithm derived cardiac stroke volume and -output.
Study context
- Population
- Mixed population of surgical patients undergoing induction of GA
- Participants
- 107 participants
- Exposure
- Peripheral Perfusion Index (PPI) decrease vs PPI increase after induction of GA
- PPI decreasedn = 38
- PPI increasedn = 69reference
- Outcome
- Relative changes of SV, CO and MAP compared to relative changes of PPI
- Follow-up
- 2 min after induction
Main finding
As reported in the abstract
MAP, SV and CO (% of baseline)
| Group | Value | Stroke volume (SV) | Cardiac output (CO) |
|---|---|---|---|
| PPI decreased | 57 (SD ± 14) % of baseline (mean arterial pressure (MAP)) | 63(± 18)% | 55(± 18)% |
| PPI increased | 70 (SD ± 15) % of baseline (MAP) | 80(± 16)% | 68(± 17)% |
Value
PPI decreased57 (SD ± 14) % of baseline (MAP)
PPI increased70 (SD ± 15) % of baseline (MAP)
Stroke volume (SV)
PPI decreased63(± 18)%
PPI increased80(± 16)%
Cardiac output (CO)
PPI decreased55(± 18)%
PPI increased68(± 17)%
- PPI decreased vs PPI increased: P < 0,001 — all differences
Observational data: associations, not effects.
Further findings
Total cohort MAP, SV, CO (% of baseline) · after induction
%
- MAP
- 65 (± 16)
- SV
- 74 (± 18)
- CO
- 63 (± 16)
- Mean(± st.dev.)
Original publication
“The peripheral perfusion index discriminates haemodynamic responses to induction of general anaesthesia”. J Clin Monit Comput. Published 8 June 2023. doi:10. 1007/ s10877-023-01035-z
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